Journal article
Relationship between retinal microstructures on optical coherence tomography and microperimetry in age-related macular degeneration
Z Wu, LN Ayton, CD Luu, RH Guymer
Ophthalmology | Published : 2014
Abstract
Purpose To determine the relationship between structural parameters of the outer retina on spectral-domain optical coherence tomography (SD-OCT) and microperimetric retinal sensitivity in early stages of age-related macular degeneration (AMD). Design Prospective, observational study. Participants Seventy-five eyes of 75 participants with early stages of AMD (drusen ≥125 μm, with/without pigmentary abnormalities) and 25 control participants of a similar age. Methods Participants underwent microperimetry testing and high-resolution SD-OCT scans. Structural parameters at 5 central points (0°, 1°, and 2.33° nasal and temporal to the fovea along the horizontal axis) corresponding to areas tested ..
View full abstractGrants
Awarded by BrightFocus Foundation
Funding Acknowledgements
Supported by the National Health and Medical Research Council (NH&MRC) Project Grant (1027624), NH&MRC practitioner fellowship (RHG, #529905), Macular Disease Foundation Australia Research Grant, Bupa Health Foundation (Australia), William Angliss (Victoria) Charitable Fund Research Grant, BrightFocus Foundation, The Perpetual Trust Foundation and MR & RA Brownless Perpetual Charitable Trust funding administered by the Trust Company. The Centre for Eye Research Australia receives Operational Infrastructure Support from the Victorian Government. This study was supported by the NH&MRC Centre for Clinical Research Excellence #529923 - Translational Clinical Research in Major Eye Diseases.