Mining surprising patterns and their explanations in clinical data

Abstract

We present a new technique for interactively mining patterns and generating explanations by harnessing the expertise of domain experts. Key to the approach is the distinction between what is unexpected from the perspective of the computational data mining process and what is surprising to the domain experts and interesting relative to their needs. We demonstrate the potential of the approach for discovering patterns and generating rich explanations in a clinical domain. Discovering interesting facts in clinical data is a grand challenge, because medical practitioners and clinicians generally have exceptional knowledge in the problem domain in which they work, however, this knowledge is typic..