Journal article

Simplified Silvestrol Analogues with Potent Cytotoxic Activity

Bill C Hawkins, Lisa M Lindqvist, Nhu Duong, Phillip P Sharp, David Segal, Andrew K Powell, Michael Campbell, Eileen Ryan, Jennifer M Chambers, Jonathan M White, Mark A Rizzacasa, Guillaume Lessene, David CS Huang, Christopher J Burns

ChemMedChem | WILEY-V C H VERLAG GMBH | Published : 2014


Awarded by Australian National Health and Medical Research Council

Funding Acknowledgements

Prof. Jonathan Baell is thanked for useful discussions, Dana Buczek is acknowledged for analytical support and H. Ierino for technical assistance. Dr. David Owen is thanked for assistance in establishing the photochemical reactor and Dr. John Flygare for samples of key intermediates and silvestrol. This work is supported by scholarships, fellowships and grants from the Australian National Health and Medical Research Council (Early Career Fellowship to L. M. L.; Research Fellowship to D. C. S. H.; program grants: 461221 and 1016701; Independent Research Institutes Infrastructure Support Scheme, grant 361646); the Victorian State Government Operational Infrastructure Support (OIS) Grant; the Australian Cancer Research Foundation; the Canadian Institutes of Health Research (Postdoctoral Fellowship to L. M. L., who is also a Bisby Fellow); Cancer Therapeutics CRC (D.N., J.M.C., M. A. R.); and Dyson Bequest funding (Dunn Fellowship to C.J.B.).