Dissecting the Insect Metabolic Machinery Using Twin Ion Mass Spectrometry: A Single P450 Enzyme Metabolizing the Insecticide Imidacloprid in Vivo
Kin Kuan Hoi, Phillip J Daborn, Paul Battlay, Charles Robin, Philip Batterham, Richard AJ O'Hair, William A Donald
Analytical Chemistry | AMER CHEMICAL SOC | Published : 2014
We thank the Australian Research Council (through the Centre of Excellence Scheme) and the School of Chemistry at the University of Melbourne (through the Chemistry Small Grants Scheme) for generous financial support. W.A.D. thanks the Faculty of Science at the University of Melbourne for the Centenary Research Fellowship and the Australian Research Council for a Discovery Early Career Researcher Award fellowship. We acknowledge Sioe See Volaric (School of Chemistry, University of Melbourne) and Paul O'Donnell (Metabolomics Australia, University of Melbourne) for helpful discussions and Dr. Ralf Nauen (Bayer CropScience AG, Monheim, Germany) for authentic metabolite standards. Acknowledgment is made to Metabolomics Australia for use of the cyromill.