Journal article
Communication of genetic test results to family and health-care providers following disclosure of research results
KD Graves, PS Sinicrope, MJ Esplen, SK Peterson, CA Patten, J Lowery, FA Sinicrope, SK Nigon, J Borgen, SS Gorin, LA Keogh, NM Lindor
Genetics in Medicine | Published : 2014
DOI: 10.1038/gim.2013.137
Abstract
Purpose: Few studies have examined methods to promote communication following the return of DNA mismatch repair genetic test results obtained during research. The purpose of the present study was to evaluate a telephone protocol for returning research results of DNA mismatch repair gene testing to identify Lynch syndrome. Methods: We invited individuals with known DNA mismatch repair mutations in their family, who were enrolled in the Colon Cancer Family Registry at the Mayo Clinic, to participate in this study. Participants completed surveys before and 6 months after DNA mismatch repair test result disclosure. Results: Among 107 participants, 79% opted to learn their DNA mismatch repair tes..
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Awarded by National Cancer Institute
Funding Acknowledgements
This work was supported by the National Cancer Institute, National Institutes of Health, under RFA #CA-95-011 and through cooperative agreements with the members of the Colon Cancer Family Registry and principal investigators. This work was further supported by NCI CAK07131172-5 (K.D.G.) and NCI P30CA051008. Portions of this work were presented at the 32nd Annual Meeting and Scientific Sessions of the Society of Behavioral Medicine, Washington, DC, April 2011. We thank the Colon Cancer Family Registry participants for their involvement in the study.