Journal article
Complete mitochondrial genomes of the 'intermediate form' of Fasciola and Fasciola gigantica, and their comparison with F. hepatica
GH Liu, RB Gasser, ND Young, HQ Song, L Ai, XQ Zhu
Parasites and Vectors | Published : 2014
Abstract
Background: Fascioliasis is an important and neglected disease of humans and other mammals, caused by trematodes of the genus Fasciola. Fasciola hepatica and F. gigantica are valid species that infect humans and animals, but the specific status of Fasciola sp. ('intermediate form') is unclear. Methods. Single specimens inferred to represent Fasciola sp. ('intermediate form'; Heilongjiang) and F. gigantica (Guangxi) from China were genetically identified and characterized using PCR-based sequencing of the first and second internal transcribed spacer regions of nuclear ribosomal DNA. The complete mitochondrial (mt) genomes of these representative specimens were then sequenced. The relationship..
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Awarded by Alexander von Humboldt-Stiftung
Funding Acknowledgements
This work was supported in part by the International Science & Technology Cooperation Program of China (Grant No. 2013DFA31840), the "Special Fund for Agro-scientific Research in the Public Interest" (Grant No. 201303037), and the Science Fund for Creative Research Groups of Gansu Province (Grant No. 1210RJIA006). RBG's research is supported by the Australian Research Council (ARC), National Health and Medical Research Council (NHMRC) and Melbourne Water Corporation (MWC); the Alexander von Humboldt Foundation is also gratefully acknowledged. This study was also supported by a Victorian Life Sciences Computation Initiative (VLSCI) grant number VR0007 on its Peak Computing Facility at the University of Melbourne, an initiative of the Victorian Government. NDY is an NHMRC Early Career Research Fellow.