Journal article
Historical epidemiology of hepatitis C virus (HCV) in selected countries
P Bruggmann, T Berg, ALH Øvrehus, C Moreno, CE Brandão Mello, F Roudot-Thoraval, RT Marinho, M Sherman, SD Ryder, J Sperl, U Akarca, I Balık, F Bihl, M Bilodeau, AJ Blasco, M Buti, F Calinas, JL Calleja, H Cheinquer, PB Christensen Show all
Journal of Viral Hepatitis | Published : 2014
DOI: 10.1111/jvh.12247
Abstract
Chronic infection with hepatitis C virus (HCV) is a leading indicator for liver disease. New treatment options are becoming available, and there is a need to characterize the epidemiology and disease burden of HCV. Data for prevalence, viremia, genotype, diagnosis and treatment were obtained through literature searches and expert consensus for 16 countries. For some countries, data from centralized registries were used to estimate diagnosis and treatment rates. Data for the number of liver transplants and the proportion attributable to HCV were obtained from centralized databases. Viremic prevalence estimates varied widely between countries, ranging from 0.3% in Austria, England and Germany ..
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Funding Acknowledgements
This work represents the contributions of many people, some of whom participated in drafting the manuscript while others contributed to the project. England-We are grateful to Daniela De Angelis, Ross Harris and Helen Harris at Public Health England for directing us to the appropriate published and unpublished data generated by Public Health England. France-Sylvie Deuffic-Burban, Henri Leleu and Martin Blachier were instrumental with our analysis of France's data. Sylvie was kind enough to share her experience and insights from her volumes of previous work. Germany-Ulrich Alshuth from Roche was kind enough to share posters and published work from the German Roche Cohort. Portugal-A number of experts provided us with their time and insights. We would like to thank the following individuals for their contribution: Dr. Alexandre Lourenco, Prof. Helena Cortez-Pinto, Dr. Joao Goulao, Luis Mendao, Prof. Paulo Ferrinho and Pedro Pita Barros. Switzerland-Virginie Masserey, Jean-Luc Richard and Christian Schaetti of the Federal Office of Public Health (FOPH) were incredibly generous with their time and data. They not only guided us to the proper datasets in Switzerland, but also ran a number of customized analyses to make this study possible. This project was supported by Gilead Sciences.