Journal article
Phenotypic differences in children conceived from fresh and thawed embryos in in vitro fertilization compared with naturally conceived children
MP Green, F Mouat, HL Miles, SA Hopkins, JGB Derraik, PL Hofman, JC Peek, WS Cutfield
Fertility and Sterility | ELSEVIER SCIENCE INC | Published : 2013
Abstract
Objective: To determine whether anthropometric and biochemical features differ in in vitro fertilization (IVF) children conceived via fresh (IVF F) or thawed (IVFT) embryo transfer compared with naturally conceived controls. Design: A cross-sectional controlled study. Setting: University clinical research unit. Patient(s): Healthy prepubertal children (3.5-11.0 years), singletons, born at term (>37 weeks), who were either naturally conceived (controls; n = 94) or IVF children conceived via the transfer of a fresh (IVFF; n = 72) or thawed (IVFT; n = 43) embryo. Intervention(s): None. Main Outcome Measure(s): Assessments of anthropometry (adjusted for parental variables), dual-energy X-ray abs..
View full abstractGrants
Funding Acknowledgements
[ "M.P.G. received a fellowship from Fertility Associates. F. M. has nothing to disclose. H. L. M. has nothing to disclose. S. A. H. has nothing to disclose. J.G.B.D. has nothing to disclose. P. L. H. has nothing to disclose. J.C.P. is a shareholder of Fertility Associates. W. S. C. has nothing to disclose.", "Supported by grants from the Gravida: National Centre for Growth and Development (NRCGD) and the Australasian Paediatric Endocrine Group (APEG).", "The authors thank the staff at the Maurice & Nessie Paykel Clinical Research Unit (The Liggins Institute, Auckland) and Fertility Associates clinics (Auckland and Hamilton) for their help with subject recruitment and testing, and the Paykel Trust for long-term funding of the Maurice & Agnes Paykel Clinical Research Unit at the Liggins Institute (University of Auckland)." ]