Journal article

Sugammadex.

Dharshi Karalapillai, Melissa Kaufman, Laurence Weinberg

Critical Care and Resuscitation | Published : 2013

Abstract

Sugammadex is the first selective antagonist to reverse neuromuscular blockade induced by rocuronium and vecuronium. The mechanism by which sugammadex works is superior to current neuromuscular block reversal strategies in terms of speed, efficacy and side effects. There is little contemporary guidance on the use of sugammadex in intensive care medicine. This review covers the key pharmacological features, clinical uses and cost- effectiveness in the context of intensive care practice.