Journal article

Differential associations of cognitive insight components with pretreatment characteristics in first-episode psychosis

Cesar Gonzalez-Blanch, Mario Alvarez-Jimenez, Rosa Ayesa-Arriola, Obdulia Martinez-Garcia, Gema Pardo-Garcia, Vicent Balanza-Martinez, Paula Suarez-Pinilla, Benedicto Crespo-Facorro



An increasing number of studies have focused on cognitive insight (i.e. awareness of one's own thinking) in psychotic disorders. However, little is known about the premorbid and pretreatment correlates of cognitive insight in the early course of psychosis. One hundred and three patients experiencing first-episode psychosis (FEP) were assessed shortly after treatment initiation for cognitive insight. Pretreatment and baseline clinical, functional and neurocognitive characteristics were examined. The self-reflectiveness dimension of cognitive insight was independently associated with clinical insight and executive functioning, whereas self-certainty was associated with premorbid IQ, premorbid ..

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Awarded by Hospital Marques de Valdecilla, University of Cantabria, Santander, Spain under Instituto de Salud Carlos III

Awarded by SENY Fundacio Research Grant

Awarded by Fundacion Marques de Valdecilla

Funding Acknowledgements

The present study was carried out at the Hospital Marques de Valdecilla, University of Cantabria, Santander, Spain, under the following grant support: Instituto de Salud Carlos III PI060507, SENY Fundacio Research Grant CI 2005-0308007 and Fundacion Marques de Valdecilla API07/011. Unrestricted educational and research grants from AstraZeneca, Pfizer, Bristol-Myers Squibb, and Johnson & Johnson provided support to PAFIP activities. This study was further supported by a grant from the Alicia Koplowitz Foundation to Dr. Gonzalez-Blanch. Dr. M. Alvarez-Jimenez is supported by the CR Roper Fellowship, Faculty of Medicine, Dentistry, and Health Science, the University of Melbourne. We wish to thank all study participants, and PAFIP staff who helped with data collection.