Journal article
Vitreous biomarkers in diabetic retinopathy: A systematic review and meta-analysis
AK McAuley, PG Sanfilippo, AW Hewitt, H Liang, E Lamoureux, JJ Wang, PP Connell
Journal of Diabetes and Its Complications | ELSEVIER SCIENCE INC | Published : 2014
Abstract
The aim of this study was to perform a systematic meta-analysis of biomarkers investigated with diabetic retinopathy (DR) in the vitreous, and to explore the molecular pathway interactions of these markers found to be consistently associated with DR. Relevant databases [PubMed and ISI web of science] were searched for all published articles investigating molecular biomarkers of the vitreous associated with DR. Based on set exclusion/inclusion criteria available data from studies with human vitreous samples were extracted and used for our meta-analysis. The interactions of significant biomarkers in DR were investigated via STRING and KEGG pathway analysis. Our meta-analysis of DR identifies e..
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Funding Acknowledgements
This research was supported by the American Health Assistance Foundation, Pfizer Australia and National Health and Medical Research Council Centre for Clinical Research Excellence Translational Clinical Research in Major Eye Diseases. AKM is supported by Australian National Health and Medical Research Council Postgraduate Scholarship.