Central injection of relaxin-3 receptor (RXFP3) antagonist peptides reduces motivated food seeking and consumption in C57BL/6J mice

Craig M Smith; Berenice E Chua; Cary Zhang; Andrew W Walker; Mouna Haidar; David Hawkes; Fazel Shabanpoor; Mohammad Akhter Hossain; John D Wade; K Johan Rosengren; Andrew L Gundlach

Journal article

Central injection of relaxin-3 receptor (RXFP3) antagonist peptides reduces motivated food seeking and consumption in C57BL/6J mice

Craig M Smith, Berenice E Chua, Cary Zhang, Andrew W Walker, Mouna Haidar, David Hawkes, Fazel Shabanpoor, Mohammad Akhter Hossain, John D Wade, K Johan Rosengren, Andrew L Gundlach

BEHAVIOURAL BRAIN RESEARCH | ELSEVIER | Published : 2014

DOI: 10.1016/j.bbr.2014.03.037

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University of Melbourne Researchers

David Hawkes Author Pharmacology and Therapeutics

Fazel Shabanpoor Author Florey Department of Neuroscience and Mental Health

Andrew Gundlach Author Anatomy and Physiology

Akhter Hossain Author Florey Department of Neuroscience and Mental Health

John Wade Author Florey Department of Neuroscience and Mental Health

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Grants

Awarded by National Health and Medical Research Council (Australia)

Funding Acknowledgements

This research was supported by National Health and Medical Research Council (Australia) project grants 509246 and 1024885 (A.L.G.) and 508995 (J.D.W.), and by the Pratt and Besen Family Foundations (A.L.G.) and the Victorian Government Operational Infrastructure Support Program. J.D.W. and A.L.G. are NHMRC (Australia) Fellows. C.Z. is the recipient of a Bethlehem Griffiths Research Foundation Scholarship, and A.W.W. is the recipient of a University of Melbourne International Scholarship (MIFRS/MIRS). We thank Steven Sutton and Timothy Lovenberg (Janssen Research and Development LLC, San Diego, USA) for providing the original colony of relaxin-3 MO mice.