Journal article

Genetic Variation in UGT Genes Modify the Associations of NSAIDs with Risk of Colorectal Cancer: Colon Cancer Family Registry

Dominique Scherer, Lisel M Koepl, Elizabeth M Poole, Yesilda Balavarca, Liren Xiao, John A Baron, Li Hsu, Anna E Coghill, Peter T Campbell, Sarah E Kleinstein, Jane C Figueiredo, Johanna W Lampe, Katharina Buck, John D Potter, Richard J Kulmacz, Mark A Jenkins, John L Hopper, Aung K Win, Polly A Newcomb, Cornelia M Ulrich Show all



Awarded by National Cancer Institute, National Institutes of Health under RFA


Funding Acknowledgements

This work was supported by the National Cancer Institute, National Institutes of Health under RFA # CA-95-011 and through cooperative agreements with members of the Colon Cancer Family Registry (CCFR) and Principal Investigators. The content of this manuscript does not necessarily reflect the views or policies of the National Cancer Institute or any of the collaborating centers in the CFRs, nor does mention of trade names, commercial products, or organizations imply endorsement by the US Government or the CFR. CFR centers providing data for the analysis include: Australasian Colorectal Cancer Family Registry (U01 CA097735); Familial Colorectal Neoplasia Collaborative Group (U01 CA074799); Mayo Clinic Cooperative Family Registry for Colon Cancer Studies (U01 CA074800); Ontario Registry for Studies of Familial Colorectal Cancer (U01 CA074783); Seattle Colorectal Cancer Family Registry (U01 CA074794); University of Hawaii Colorectal Cancer Family Registry (U01 CA074806); and University of California, Irvine Informatics Center (U01 CA078296). We thank Allyson Templeton for providing us with data on CCFR enrollment and follow-up. We also thank Sushma Thomas, Christine Rimorin, Jeanne DaGloria, and Ling-Yu Kuan of the FHCRC Molecular Epidemiology Laboratory for genotyping assistance.