Thrombolysis ImPlementation in Stroke (TIPS): evaluating the effectiveness of a strategy to increase the adoption of best evidence practice - protocol for a cluster randomised controlled trial in acute stroke care
Christine L Paul, Christopher R Levi, Catherine A D'Este, Mark W Parsons, Christopher F Bladin, Richard I Lindley, John R Attia, Frans Henskens, Erin Lalor, Mark Longworth, Sandy Middleton, Annika Ryan, Erin Kerr, Robert W Sanson-Fisher
Implementation Science | BMC | Published : 2014
Awarded by National Health and Medical Research Council (NHMRC)
This project is funded by the National Health and Medical Research Council (NHMRC) as a partnership grant (ID569328) and is part-funded by a TRIP fellowship, with collaborative funding from Boehringer Ingelheim and in-kind support from ACI Stroke Care Network/Stroke Services NSW, Victorian Stroke Clinical Network, National Stroke Foundation (NSF) and NSW Cardiovascular Research Network-National Heart Foundation, with infrastructure funding from Hunter Medical Research Institute (HMRI) and The University of Newcastle (UoN). The UoN is the coordinating centre, the TRIP fellowship funds the research activities for the Clinical Champion, Boehringer Ingelheim funds workshops, logistics and educational material, ACI Stroke Clinical Network/Stroke Services NSW and Victorian Stroke Clinical Network provide support for a stroke care coordinator's time collating and entering tPA audit results, and NSW Cardiovascular Research Network-National Heart Foundation provides support for the involvement of a clinical practice change expert to support quality improvement strategies at each site. The NHMRC partnership grant is covering the cost of the remaining project activities. Although the Industry Partner is a manufacturer of the tPA drug and therefore has a vested interest in increasing tPA rates, their involvement is subject to strict guidelines, including non-involvement in the study design, data collection, analysis and publications. The assistance of Kate Day and Kate Ross in progressing toward launching the study is gratefully acknowledged.