The PACE study: A randomized clinical trial of cognitive activity strategy training for older people with mild cognitive impairment

Abstract

Objective The role of cognition-focused interventions in reducing cognitive decline in older people remains uncertain. This study aimed to clarify whether a group cognitive activity (CA) strategy-training program would decrease the 2-year rate of cognitive decline of people with mild cognitive impairment (MCI). Design Randomized controlled trial. Setting One study site. Participants 160 older adults with MCI ≥ 65 years of age (mean: 75, SD: 5.8). Intervention Five-week CA strategy training or a control nonspecific educational program. The primary outcome measure was change from baseline in the total score on the Cambridge Cognitive Examination-Revised (CAMCOG-R). Secondary outcomes of inte..