Birinapant, a Smac-Mimetic with Improved Tolerability for the Treatment of Solid Tumors and Hematological Malignancies
Stephen M Condon, Yasuhiro Mitsuuchi, Yijun Deng, Matthew G LaPorte, Susan R Rippin, Thomas Haimowitz, Matthew D Alexander, Pavan Tirunahari Kumar, Mukta S Hendi, Yu-Hua Lee, Christopher A Benetatos, Guangyao Yu, Gurpreet Singh Kapoor, Eric Neiman, Martin E Seipel, Jennifer M Burns, Martin A Graham, Mark A McKinlay, Xiaochun Li, Jiawei Wang Show all
Journal of Medicinal Chemistry | AMER CHEMICAL SOC | Published : 2014
Awarded by NHMRC
The authors acknowledge the support from our colleagues at TetraLogic Pharmaceuticals (Malvern, PA) and our co-workers at the START Preclinical Research Group (San Antonio, TX) and the Piedmont Research Center, LLC (Morrisville, NC) for conducting the animal experiments described in this paper. J.S. was supported by NHMRC grants (Grants 433013, 541902, 461221, 1046986) and fellowships (Grant 541901). C.L.D. acknowledges financial support from the Health Research Council of New Zealand. We thank C. Glenn Begley for critical reading of this manuscript.