Journal article
Working towards a Group A Streptococcal vaccine: Report of a collaborative Trans-Tasman workshop
NJ Moreland, CS Waddington, DA Williamson, S Sriskandan, PR Smeesters, T Proft, AC Steer, MJ Walker, EN Baker, MG Baker, D Lennon, R Dunbar, J Carapetis, JD Fraser
Vaccine | Published : 2014
Abstract
Group A Streptococcus (GAS) infections represent a major public health burden in both developing and developed countries. In Australia and New Zealand GAS associated diseases are serious problems in Indigenous populations and a major cause of health inequality. Political recognition of these inequalities is providing impetus for strategies that reduce GAS disease and the development of a GAS vaccine now has governmental support in both Australia and New Zealand. Accordingly, an expert workshop was convened in March 2013 to consider available data on GAS vaccines. M-protein based vaccines constructed from the hyper-variable N-terminal region (30-valent vaccine) or the conserved C-repeat domai..
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Awarded by Medical Research Council
Funding Acknowledgements
We thank all the individuals who freely gave their time to participate in the Trans-Tasman GAS vaccine workshop that formed the basis of this article. The Maurice Wilkins Centre supported the workshop and NM is a New Zealand Heart Foundation (grant no. 1465) research fellow. We also thank Vivian Ward for assistance in preparing the illustration.