Journal article

More rigorous protocol adherence to intensive structured management improves blood pressure control in primary care: Results from the Valsartan Intensified Primary carE Reduction of Blood Pressure study

S Stewart, NP Stocks, LM Burrell, FJ De Looze, A Esterman, M Harris, J Hung, CH Swemmer, NP Kurstjens, GL Jennings, MJ Carrington

Journal of Hypertension | Published : 2014

Abstract

Objective: To examine protocol adherence to structured intensive management in the Valsartan Intensified Primary carE Reduction of Blood Pressure (VIPER-BP) study involving 119 primary care clinics and 1562 randomized participants. Methods: Prospective criteria for assessing adherence to treatment prescription, uptitration, and visit attendance at 6, 10, 14, and 18 weeks postrandomization were applied to 1038 intervention participants. Protocol adherence scores of 1-5 (least to most adherent) were compared to blood pressure (BP) control during 26 weeks of follow-up. Results: Mean age was 59.3±12.0 years, 963 (62%) were men, and 1045 (67%) had longstanding hypertension. Clinic attendance drop..

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University of Melbourne Researchers

Grants

Funding Acknowledgements

S.S., G.L.J., and M.C. are supported by the National Health and Medical Research Council of Australia. The VIPER-BP study was sponsored by Novartis Pharmaceuticals Australia Ltd. and was supported in part by the Victorian Government's Operational Infrastructure Support Program.