Journal article

A COMPARISON OF THE PREDICTIVE ACCURACY OF THREE SCREENING MODELS (DETECT V. ESC/ERS V. ASIG) FOR PULMONARY ARTERIAL HYPERTENSION IN SYSTEMIC SCLEROSIS

Y Hao, V Thakkar, W Stevens, K Morrisroe, D Prior, C Rabusa, P Youssef, E Gabbay, J Roddy, J Walker, J Zochling, J Sahhar, P Nash, S Lester, M Rischmueller, S Proudman, M Nikpour

INTERNAL MEDICINE JOURNAL | WILEY-BLACKWELL | Published : 2014

Abstract

INTRODUCTION: There is evidence that early screening for pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc) improves outcomes. We compared the predictive accuracy of two recently published screening algorithms (DETECT 2013 and Australian Scleroderma Interest Group (ASIG) 2012) for SSc-associated PAH (SSc-PAH) with the commonly used European Society of Cardiology/European Respiratory Society (ESC/ERS 2009) guidelines. METHODS: We included 73 consecutive SSc patients with suspected PAH undergoing right heart catheterization (RHC). The three screening models were applied to each patient. For each model, contingency table analysis was used to determine sensitivity, specificity, an..

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