Journal article

Surgical margins in head and neck cancer: A contemporary review

Michael L Hinni, Alfio Ferlito, Margaret S Brandwein-Gensler, Robert P Takes, Carl E Silver, William H Westra, Raja R Seethala, Juan P Rodrigo, June Corry, Carol R Bradford, Jennifer L Hunt, Primoz Strojan, Kenneth O Devaney, Douglas R Gnepp, Dana M Hartl, Luiz P Kowalski, Alessandra Rinaldo, Leon Barnes

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | WILEY | Published : 2013

Abstract

Adequate resection margins are critical to the treatment decisions and prognosis of patients with head and neck squamous cell carcinoma (HNSCC). However, there are numerous controversies regarding reporting and interpretation of the status of resection margins. Fundamental issues relating to the basic definition of margin adequacy, uniform reporting standards for margins, optimal method of specimen dissection, and the role of intraoperative frozen section evaluation, all require further clarification and standardization. Future horizons for margin surveillance offer the possible use of novel methods such as "molecular margins" and contact microscopic endoscopy, However, the limitations of th..

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University of Melbourne Researchers