Journal article

Analysis of 1 year virtual histology changes in coronary plaque located behind the struts of the everolimus eluting bioresorbable vascular scaffold

Salvatore Brugaletta, Josep Gomez-Lara, Hector M Garcia-Garcia, Jung Ho Heo, Vasim Farooq, Robert J van Geuns, Bernard Chevalier, Stephan Windecker, Dougal McClean, Leif Thuesen, Robert Whitbourn, Ian Meredith, Cecile Dorange, Susan Veldhof, Richard Rapoza, John A Ormiston, Patrick W Serruys

International Journal of Cardiovascular Imaging | SPRINGER | Published : 2012

Abstract

Serial intravascular ultrasound virtual histology (IVUS-VH) after implantation of metallic stents has been unable to show any changes in the composition of the scaffolded plaque overtime. The everolimus-eluting ABSORB scaffold potentially allows for the formation of new fibrotic tissue on the scaffolded coronary plaque during bioresorption. We examined the 12 month IVUS-VH changes in composition of the plaque behind the struts (PBS) following the implantation of the ABSORB scaffold. Using IVUS-VH and dedicated software, the composition of the PBS was analyzed in all patients from the ABSORB Cohort B2 trial, who were imaged with a commercially available IVUS-VH console (s5i system, Volcano Co..

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