Journal article

Altered methylation of the human MDR1 promoter is associated with acquired multidrug resistance

P Kantharidis, A ElOsta, M deSilva, DMP Wall, XF Hu, A Slater, G Nadalin, JD Parkin, JR Zalcberg

Clinical Cancer Research | AMER ASSOC CANCER RESEARCH | Published : 1997

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Keywords

Cpg Methylation
Drug Resistance, Multiple
Dna Methylation
Azacitidine
Verapamil
Atp Binding Cassette Transporter, Subfamily B, Member 1
Expression
Restriction Mapping
Transcription, Genetic
Dinucleoside Phosphates
Leukemia, T-Cell
Tumor Cells, Cultured
Daunorubicin
Promoter Regions, Genetic
Epirubicin
Cell-Lines
Science & Technology
Binding
Leukemia, Lymphocytic, Chronic, B-Cell
Oncology
Sp1
Humans
Decitabine
Introns
Blotting, Southern
P-Glycoprotein
Life Sciences & Biomedicine
Transcription
Exons
Antimetabolites, Antineoplastic
Up-Regulation
Polymerase Chain-Reaction
Tumor-Suppressor Gene