Journal article

Modulation of the function of human MDR1 P-glycoprotein by the antimalarial drug mefloquine

CD Riffkin, R Chung, DM Wall, JR Zalcberg, AF Cowman, M Foley, L Tilley

Biochemical Pharmacology | PERGAMON-ELSEVIER SCIENCE LTD | Published : 1996

DOI: 10.1016/S0006-2952(96)00556-4

Citation metrics

48Web of Science
54Scopus

Keywords

Kinetics
Binding, Competitive
Multidrug Resistance
Pharmacology & Pharmacy
Mefloquine
Vinblastine
Life Sciences & Biomedicine
Cell Line K562/adm
Affinity Labels
Chloroquine
Science & Technology
Biological Transport, Active
Prophylaxis
Atp Binding Cassette Transporter, Subfamily B, Member 1
Drug Resistance, Multiple
Antimalarials
Multidrug-Resistance
Quinine
Prazosin
Fluorescent Dyes
Binding Sites
Quinoline Antimalarials
Tumor Cells, Cultured
Cyclosporine-A
Daunorubicin
Blood-Brain-Barrier
Human-Leukemic Lymphoblasts
Verapamil
Drug Interactions
P-Glycoprotein
Neoplasms
Humans