Journal article

SKIN-CANCER AND HLA ANTIGENS

D CZARNECKI, J ZALCBERG, I NICHOLSON, B TAIT

NEW ENGLAND JOURNAL OF MEDICINE | MASS MEDICAL SOC | Published : 1992

Abstract

To the Editor: The study by Bouwes Bavinck and colleagues on the relation between skin cancers and HLA antigens in renal-transplant recipients (Sept. 19 issue)1 offers further support to the notion that genetic background, immunologic responses, and environmental factors all contribute to the development of skin cancers in humans. Although the authors found an association between mismatching for HLA-B and an increased risk of squamous-cell carcinoma, they observed no such relation in the 18 patients with basal-cell carcinoma. The lack of an association between any HLA antigen and basal-cell carcinoma is not surprising, since the number of patients with this. © 1992, Massachusetts Medical Soc..

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