Structural Basis for Par-4 Recognition by the SPRY Domain- and SOCS Box-Containing Proteins SPSB1, SPSB2, and SPSB4
Panagis Filippakopoulos, Andrew Low, Timothy D Sharpe, Jonas Uppenberg, Shenggen Yao, Zhihe Kuang, Pavel Savitsky, Rowena S Lewis, Sandra E Nicholson, Raymond S Norton, Alex N Bullock
Journal of Molecular Biology | ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD | Published : 2010
Awarded by National Health and Medical Research Council, Australia
Awarded by National Health and Medical Research Council
Awarded by Canadian Institutes for Health Research
This work was supported in part by the National Health and Medical Research Council, Australia (Program grant 461219 and Project grant 461233 to R.S.N. and S.E.N., fellowships to R.S.N. and S.E.N., and a National Health and Medical Research Council IRIISS grant 361646), as well as a Victorian State Government OIS grant. We thank Brian Smith for his assistance with the molecular dynamics simulations. We thank Frank von Delft as well as staff at the Swiss Light Source and Diamond synchrotrons for assistance with diffraction data collection. The Structural Genomics Consortium is a registered charity (number 1097737) that receives funds from the Canadian Institutes for Health Research, the Canadian Foundation for Innovation, Genome Canada through the Ontario Genomics Institute, GlaxoSmithKline, Karolinska Institutet, the Knut and Alice Wallenberg Foundation, the Ontario Innovation Trust, the Ontario Ministry for Research and Innovation, Merck & Co Inc., the Novartis Research Foundation, the Swedish Agency for Innovation Systems, the Swedish Foundation for Strategic Research, and the Wellcome Trust.