Journal article

A variant of KCC2 from patients with febrile seizures impairs neuronal Cl- extrusion and dendritic spine formation

Martin Puskarjov, Patricia Seja, Sarah E Heron, Tristiana C Williams, Faraz Ahmad, Xenia Iona, Karen L Oliver, Bronwyn E Grinton, Laszlo Vutskits, Ingrid E Scheffer, Steven Petrou, Peter Blaesse, Leanne M Dibbens, Samuel F Berkovic, Kai Kaila

EMBO REPORTS | WILEY-BLACKWELL | Published : 2014

Grants

Awarded by Innovative Medical Research Fund of the University of Munster Medical School


Awarded by Swiss National Science Foundation


Awarded by National Health and Medical Research Council of Australia


Awarded by Early Career Fellowship


Awarded by Career Development Fellowship


Funding Acknowledgements

We thank the patients and their families for participating in our research. We would like to acknowledge David B. Mount for providing the human KCC2 clone and Merle Kampura, Michelle Brunet, Timea Bodogan, Bev Johns and Robert Schultz for excellent technical assistance. This work was supported by the Academy of Finland (PB and KK), the Sigrid Juselius Foundation (KK), the Jane and Aatos Erkko Foundation (KK), Innovative Medical Research Fund of the University of Munster Medical School (I-BL211215 PB), the Swiss National Science Foundation (Grant 310030-146201 LV), and the National Health and Medical Research Council of Australia (Program Grant 628952 SFB, LMD, IES and SP; Early Career Fellowship 1016715 SHE and Career Development Fellowship 1032603 LMD).