Aspirin and clonidine in non-cardiac surgery: acute kidney injury substudy protocol of the Perioperative Ischaemic Evaluation ( POISE) 2 randomised controlled trial
Amit X Garg, Andrea Kurz, Daniel I Sessler, Meaghan Cuerden, Andrea Robinson, Marko Mrkobrada, Chirag Parikh, Richard Mizera, Philip M Jones, Maria Tiboni, Raul Gonzalez Rodriguez, Ekaterina Popova, Maria Fernanda Rojas Gomez, Christian S Meyhoff, Tomas Vanhelder, Matthew TV Chan, David Torres, Joel Parlow, Miriam de Nadal Clanchet, Mohammed Amir Show all
BMJ Open | BMJ PUBLISHING GROUP | Published : 2014
Awarded by Canadian Institutes of Health Research
Awarded by NATIONAL CANCER INSTITUTE
The POISE-2 trial and the AKI substudy are funded by two grants from the Canadian Institutes of Health Research (application number of the AKI substudy: 259720). General support for POISE-2 was also provided by the Australian National Health and Medical Research Council and the Spanish Ministry of Health and Social Policy. Boehringer Ingelheim provided the clonidine study drug and some funding, and Bayer Schering Pharma provided the aspirin study drug. The sponsors of POISE-2 and the AKI substudy had no role in the design and conduct of the study; collection, management, analysis and interpretation of the data; preparation, review or approval of this protocol paper; and decision to submit this protocol manuscript for publication.