Conservative Oxygen Therapy in Mechanically Ventilated Patients: A Pilot Before-and-After Trial
Satoshi Suzuki, Glenn M Eastwood, Neil J Glassford, Leah Peck, Helen Young, Mercedes Garcia-Alvarez, Antoine G Schneider, Rinaldo Bellomo
CRITICAL CARE MEDICINE | LIPPINCOTT WILLIAMS & WILKINS | Published : 2014
OBJECTIVES: To assess the feasibility and safety of a conservative approach to oxygen therapy in mechanically ventilated ICU patients. DESIGN: Pilot prospective before-and-after study. SETTING: A 22-bed multidisciplinary ICU of a tertiary care hospital in Australia. PATIENTS: A total of 105 adult (18 years old or older) patients required mechanical ventilation for more than 48 hours: 51 patients during the "conventional" before period and 54 after a change to "conservative" oxygen therapy. INTERVENTIONS: Implementation of a conservative approach to oxygen therapy (target SpO2 of 90-92%). MEASUREMENTS AND MAIN RESULTS: We collected 3,169 datasets on 799 mechanical ventilation days. During con..View full abstract
Supported, in part, by the Austin Hospital Intensive Care Trust Fund.