Journal article

Conservative Oxygen Therapy in Mechanically Ventilated Patients: A Pilot Before-and-After Trial

Satoshi Suzuki, Glenn M Eastwood, Neil J Glassford, Leah Peck, Helen Young, Mercedes Garcia-Alvarez, Antoine G Schneider, Rinaldo Bellomo

CRITICAL CARE MEDICINE | LIPPINCOTT WILLIAMS & WILKINS | Published : 2014

Abstract

OBJECTIVES: To assess the feasibility and safety of a conservative approach to oxygen therapy in mechanically ventilated ICU patients. DESIGN: Pilot prospective before-and-after study. SETTING: A 22-bed multidisciplinary ICU of a tertiary care hospital in Australia. PATIENTS: A total of 105 adult (18 years old or older) patients required mechanical ventilation for more than 48 hours: 51 patients during the "conventional" before period and 54 after a change to "conservative" oxygen therapy. INTERVENTIONS: Implementation of a conservative approach to oxygen therapy (target SpO2 of 90-92%). MEASUREMENTS AND MAIN RESULTS: We collected 3,169 datasets on 799 mechanical ventilation days. During con..

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