Journal article
Focal abnormalities in idiopathic generalized epilepsy: A critical review of the literature
U Seneviratne, M Cook, W D'Souza
Epilepsia | Published : 2014
DOI: 10.1111/epi.12688
Abstract
Summary Conventionally, epilepsy is dichotomized into distinct "focal" and "generalized" categories. However, many studies have reported so-called focal features among patients with idiopathic generalized epilepsy (IGE) in the domains of semiology, electroencephalography, neuropsychology, neuropathology, and neuroimaging. We sought to review such features and clinical implications. A Web of Science database search was conducted to identify relevant publications. Our search yielded 145 papers describing focal features involving different domains in IGE, with 117 papers analyzed after excluding abstracts and case reports. Focal semiologic features are commonly seen in IGE. There are conflictin..
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Funding Acknowledgements
A/Professor D'Souza has received travel, investigator-initiated, and speaker honoraria from UCB Pharma; educational grants from Novartis Pharmaceuticals and Pfizer Pharmaceuticals; educational, travel, and fellowship grants from GlaxoSmithKline Neurology Australia; and honoraria from SciGen Pharmaceuticals. Professor Cook has received speaker honoraria from UCB Pharma and Sanofi Australia and travel honoraria from UCB Pharma and SciGen. He has received research grants from National Health and Medical Research Council (Australia), and Australian Research Council. He has also received a Science, Technology, and Innovation Grant from the State Government of Victoria, Australia. Dr. Seneviratne has received an educational grant and speaker honoraria from UCB Pharma. We confirm that we have read the Journal's position on issues involved in ethical publication and affirm that this report is consistent with those guidelines.