Journal article

DIAGNOSIS OF FELINE LEUKEMIA-VIRUS AND FELINE IMMUNODEFICIENCY VIRUS-INFECTIONS

BW PARRY, SA HOLLOWAY, MJ STUDDERT

VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE | W B SAUNDERS CO | Published : 1989

Abstract

Feline leukemia virus is an oncogenic retrovirus that can result in a wide variety of neoplastic and non-neoplastic diseases, including immunosuppression. Diagnosis of FeLV infection can be achieved by several methods, including virus isolation; IFA assay of a peripheral blood smear; and detection of a viral protein (called p27) by ELISA testing of whole blood, plasma, serum, saliva, or tears. Commercially available ELISA kits have revolutionized FeLV testing and have become very popular as "in-house" procedures. This article discusses the interpretation of ELISA results and compares them with IFA assay findings. Feline immunodeficiency virus is a lentivirus that causes immunosuppression, bu..

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