Journal article

Low Testosterone in Men with Type 2 Diabetes: Significance and Treatment

Mathis Grossmann

The Journal of Clinical Endocrinology & Metabolism | ENDOCRINE SOC | Published : 2011


CONTEXT: The relationship between testosterone and diabetes in men is an important issue, given that one third of U.S. men aged 65 yr or older have diabetes, with a similar percentage having low testosterone levels. EVIDENCE ACQUISITION: The medical literature from 1970 to March 2011 was reviewed for key articles. EVIDENCE SYNTHESIS: In population-based studies, low testosterone is commonly associated with type 2 diabetes and the metabolic syndrome, and it identifies men with an adverse metabolic profile. The difference in testosterone levels between men with diabetes compared to men without diabetes is moderate and comparable in magnitude to the effects of other chronic diseases, suggesting..

View full abstract

University of Melbourne Researchers


Funding Acknowledgements

This work was supported by the National Health and Medical Research Council of Australia and by the Royal Australasian College of Physicians.I am the principal investigator of an investigator-initiated trial assessing the effects of testosterone therapy in men with type 2 diabetes and low testosterone levels supported by Bayer Schering Pharma AG, Berlin, Germany.