Journal article

Longitudinal study of risk factors for coronary heart disease across the menopausal transition

KA Do, A Green, JR Guthrie, EC Dudley, HG Burger, L Dennerstein

American Journal of Epidemiology | JOHNS HOPKINS UNIV SCHOOL HYGIENE PUB HEALTH | Published : 2000


The patterns of change in blood lipids, diastolic blood pressure, body mass index, smoking and drinking behaviors, and exercise were examined in an ongoing longitudinal study from 1991 to 1995 of 150 middle-aged Melbourne, Australia, women as they passed through menopause. Changes in risk factors over time were examined with reference to time of the final menstrual period (FMP). Random effects models were fitted with adjustments for repeated measures and other covariates, including age. There were overall net increases between 3 years before and the 3 years after menopause of 0.25 mmol/liter for low density lipoprotein cholesterol, 0.05 mmol/liter for high density lipoprotein cholesterol (HD..

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University of Melbourne Researchers