Journal article

A prospective population-based study of menopausal symptoms

L Dennerstein, EC Dudley, JL Hopper, JR Guthrie, HG Burger

Obstetrics and Gynecology | LIPPINCOTT WILLIAMS & WILKINS | Published : 2000


OBJECTIVE: To identify symptoms that change in prevalence and severity during midlife and evaluate their relationships to menopausal status, hormonal levels, and other factors. METHODS: In a longitudinal, population-based study of 438 Australian-born women observed for 7 years with an 89% retention rate, 172 advanced from premenopause to perimenopause or postmenopause. Annual measures included a 33-item symptom check list; psychosocial, lifestyle, and health-related factors; menstrual status; hormone usage; and blood levels of follicle-stimulating hormone and estradiol (E2). RESULTS: Increasing from early to late perimenopause were the number of women who reported five or more symptoms (+14%..

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