Journal article

A prospective study of bone loss in menopausal Australian-born women

JR Guthrie, PR Ebeling, JL Hopper, E Barrett-Connor, L Dennerstein, EC Dudley, HG Burger, JD Wark

Osteoporosis International | SPRINGER-VERLAG LONDON LTD | Published : 1998


Two hundred and twenty-four women (74 pre-, 90 peri-, 60 post-menopausal), aged 46-59 years, from a population-based cohort participated in a longitudinal study of bone mineral density (BMD). BMD was measured by dual-energy X-ray absorptiometry (DXA) at the lumbar spine and femoral neck and the time between bone scans was on average 25 (range 14-41) months. The aim of the study was to assess changes in BMD in relation to changes in normal menopausal status. During the study period women who were between 3 and 12 months past their last menstrual period (n = 22, late perimenopausal) at the time of the second bone scan had a mean (SE) annual change in BMD of -0.9% (0.4%) at the lumbar spine and..

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