Journal article

Volumetric and visual assessment of the mesial temporal structures in Alzheimer's disease

PM Desmond, JT O'Brien, BM Tress, DJ Ames, JG Clement, P Clement, I Schweitzer, V Tuckwell, GS Robinson

Australian and New Zealand Journal of Medicine | ADIS PRESS AUSTRALASIA P/L | Published : 1994

Abstract

Background: Alzheimer's disease is the commonest cause of dementia. Clinical diagnosis of Alzheimer's disease may be difficult. Magnetic resonance imaging has a role to play in diagnosis. Aim: To assess whether volumetric and/or visual assessment of the mesial temporal structures is useful in separating patients with Alzheimer's disease from age matched controls. Methods: Twenty‐four patients with Alzheimer's disease diagnosed by NINCDS/ADRDA criteria and 15 age matched controls were studied with magnetic resonance imaging (MRI) and volumetric techniques. Segmented volumes of the mesial temporal structures were assessed visually and volumetrically. Results: Volumetric analysis demonstrated s..

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