Spontaneous liver hemorrhage during laparotomy for necrotizing enterocolitis: A potential role for recombinant factor VIIa

Abstract

Necrotizing enterocolitis remains a serious condition in very low birth weight infants, particularly in those infants who require surgery. Perioperative hemorrhage is a potentially fatal complication in this population. We describe our experience in 4 premature infants with necrotizing enterocolitis who received recombinant factor VIIa to manage life-threatening intraoperative hemorrhage. Copyright © 2005 Elsevier Inc. All rights reserved.