Journal article

Efficacy of furosemide for prevention of exercise-induced pulmonary hemorrhage in Thoroughbred racehorses

Kenneth W Hinchcliff, Paul S Morley, Alan J Guthrie

Journal of the American Veterinary Medical Association | AMER VETERINARY MEDICAL ASSOC | Published : 2009

Abstract

OBJECTIVE: To evaluate the efficacy of furosemide for prevention of exercise-induced pulmonary hemorrhage (EIPH) in Thoroughbred racehorses under typical racing conditions. DESIGN: Randomized, placebo-controlled, blinded, crossover field trial. ANIMALS: 167 Thoroughbred racehorses. PROCEDURES: Horses were allocated to race fields of 9 to 16 horses each and raced twice, 1 week apart, with each of the 2 races consisting of the same race field and distance. Each horse received furosemide (500 mg, IV) before one race and a placebo (saline solution) before the other, with the order of treatments randomly determined. Severity of EIPH was scored on a scale from 0 to 4 after each race by means of tr..

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Grants

Funding Acknowledgements

Supported by the National Horseracing Authority of South Africa, Phumelela Gaming and Leisure (Pty) Ltd, TecMed (Pty) Ltd, Racing South Africa (Pty) Ltd, the Grayson-jockey Club Research Foundation, the Racing Medication and Testing Consortium, the Thoroughbred Racing Trust of South Africa, and private donors.