Positron emission tomography and epilepsy

Abstract

Purpose: This review examines the current role of positron emission tomography (PET) in the investigation and management of patients with epilepsy. Procedures: A literature review utilizing MEDLINE® and other sources was undertaken. For the comparison of the accuracy of PET with magnetic resonance imaging (MRI) for seizure focus localization, only publications since 1994 were examined. Individual patient data was tabulated to provide figures for seizure focus localization rates for different types of focal epilepsy and the prognostic value of PET findings for epilepsy surgery outcome. Results: The majority of PET studies used 2-deoxy-2-[18F]fluoro-D-glucose (FDG). The epileptogenic sites typ..