Journal article

Evaluation of the perioperative analgesic efficacy of buprenorphine, compared with butorphanol, in cats

Leon N Warne, Thierry Beths, Merete Holm, Jennifer E Carter, Sebastien H Bauquier

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION | AMER VETERINARY MEDICAL ASSOC | Published : 2014

Abstract

OBJECTIVE: To compare the analgesic effects of buprenorphine and butorphanol in domestic cats. DESIGN: 2-phase positive-controlled randomized masked clinical trial. ANIMALS: 39 healthy female cats (10 in phase 1 and 29 in phase 2). PROCEDURES: Cats admitted for ovariohysterectomy received buprenorphine (4 in phase 1; 14 in phase 2) or butorphanol (6 in phase 1; 15 in phase 2). In phase 1, cats were premedicated with buprenorphine (0.02 mg/kg [0.009 mg/lb], IM) or butorphanol (0.4 mg/kg [0.18 mg/lb], IM), in combination with medetomidine. Anesthesia was induced with propofol (IV) and maintained with isoflurane in oxygen. After extubation, medetomidine was antagonized with atipamezole. A valid..

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