Tolerance and Immunity to the Ro/La RNP Complex

Abstract

This chapter contains sections titled: Introduction The Nature of the Autoimmune Response to La The Ro/La Ribonucleoprotein Complex Autoimmune Findings in Humans Autoimmunity to La in Experimental Models Tolerance to Nuclear Antigens Lack of Tolerance in the B‐cell Compartment Tolerance in the T‐cell Compartment Induction of Disease Anti‐La Autoantibodies Are Pathogenic in the Neonatal Lupus Syndrome Concluding Remarks Introduction The Nature of the Autoimmune Response to La The Ro/La Ribonucleoprotein Complex Autoimmune Findings in Humans Autoimmunity to La in Experimental Models Tolerance to Nuclear Antigens Lack of Tolerance in the B‐cell Compartment Tolerance in the T‐cell Compartment In..