Journal article

Oral contraceptives and bone mineral density: A population-based study

JA Pasco, MA Kotowicz, MJ Henry, S Panahi, E Seeman, GC Nicholson

American Journal of Obstetrics and Gynecology | MOSBY-YEAR BOOK INC | Published : 2000


OBJECTIVE: We sought to test the hypothesis that exposure to oral contraceptives protects the skeleton. STUDY DESIGN: Multiple regression techniques were used to analyze data for a random sample of 710 Australian women (age range, 20-69 years). Bone mineral density was measured at the lumbar spine, proximal femur, whole body, and distal forearm. Oral contraceptive exposure was assessed by a questionnaire. RESULTS: Women exposed to oral contraceptives had a 3.3% greater mean bone mineral density adjusted for body mass index and age at the lumbar spine (partial r (2) = 0.009; P =.014). Adjusted mean vertebral bone mineral density was 3.3% greater for premenopausal women (partial r (2) = 0.008;..

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University of Melbourne Researchers