Journal article

The effects of polarizing current on nerve terminal impulses recorded from polymodal and cold receptors in the guinea-pig cornea

RW Carr, S Pianova, JA Brock

JOURNAL OF GENERAL PHYSIOLOGY | ROCKEFELLER UNIV PRESS | Published : 2002

Abstract

It was reported recently that action potentials actively invade the sensory nerve terminals of corneal polymodal receptors, whereas corneal cold receptor nerve terminals are passively invaded (Brock, J.A., S. Pianova, and C. Belmonte. 2001. J. Physiol. 533:493-501). The present study investigated whether this functional difference between these two types of receptor was due to an absence of voltage-activated Na(+) conductances in cold receptor nerve terminals. To address this question, the study examined the effects of polarizing current on the configuration of nerve terminal impulses recorded extracellularly from single polymodal and cold receptors in guinea-pig cornea isolated in vitro. Po..

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University of Melbourne Researchers