Journal article

Duration of red blood cells storage and outcome in critically ill patients

Cecile Aubron, Michael Bailey, Zoe McQuilten, David Pilcher, Colin Hegarty, Anthony Martinelli, Geoff Magrin, David Irving, D Jamie Cooper, Rinaldo Bellomo

Journal of Critical Care | W B SAUNDERS CO-ELSEVIER INC | Published : 2014


PURPOSE: There is conflicting evidence on the effect of red blood cells (RBC) storage duration and clinical outcomes. We aimed to investigate the association between RBC storage duration and clinical outcomes in patients admitted to the intensive care unit (ICU). MATERIALS AND METHODS: We retrospectively (2001-2011) studied adults admitted to the ICUs of 2 hospitals who received RBC. Using the mean, maximum and minimum age of RBC units transfused, we evaluated the association between RBC storage duration and mortality. We also analyzed the association between mean age of RBC units and length of stay (LOS) in survivors. We performed sensitivity analyses in patients who only received RBC in IC..

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University of Melbourne Researchers