Fundamental Differences in Electrophysiologic and Electroanatomic Substrate Between Ischemic Cardiomyopathy Patients With and Without Clinical Ventricular Tachycardia

HM Haqqani; JM Kalman; KC Roberts-Thomson; RN Balasubramaniam; R Rosso; RL Snowdon; PB Sparks; JK Vohra; JB Morton

Journal article

Fundamental Differences in Electrophysiologic and Electroanatomic Substrate Between Ischemic Cardiomyopathy Patients With and Without Clinical Ventricular Tachycardia

HM Haqqani, JM Kalman, KC Roberts-Thomson, RN Balasubramaniam, R Rosso, RL Snowdon, PB Sparks, JK Vohra, JB Morton

Journal of the American College of Cardiology | ELSEVIER SCIENCE INC | Published : 2009

DOI: 10.1016/j.jacc.2009.04.024

Abstract

Objectives: The aim of this study was to compare the electrophysiologic substrate in ischemic cardiomyopathy (ICM) patients with and without sustained monomorphic ventricular tachycardia (SMVT). Background: Despite the universal presence of potentially arrhythmogenic left ventricular (LV) scarring, it is not clear why the majority of ICM patients never develop SMVT. Methods: Detailed electroanatomic mapping of the LV endocardium was performed in 17 stable control ICM patients (16 males) without clinical SMVT. They were compared with 17 ICM patients (15 males) with spontaneous SMVT. Standard definitions of low-voltage zones and fractionated, isolated, and very late potentials were used. Resul..

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University of Melbourne Researchers

Jonathan Kalman Author

Jitendra Vohra Author

Grants

Funding Acknowledgements

From the Department of Cardiology, Royal Melbourne Hospital and the Department of Medicine, University of Melbourne, Melbourne, Australia. Drs. Haqqani and Roberts-Thomson are the recipients of Postgraduate Medical Scholarships from the National Health and Medical Research Council of Australia as well as Cardiovascular Lipid Grants.