Journal article

Electrical remodelling of the left and right atria due to rheumatic mitral stenosis

B John, MK Stiles, P Kuklik, ST Chandy, GD Young, L MacKenzie, L Szumowski, G Joseph, J Jose, SG Worthley, JM Kalman, P Sanders

European Heart Journal | OXFORD UNIV PRESS | Published : 2008

Abstract

Aims: To characterize the atrial remodelling in mitral stenosis (MS). Methods and results: Twenty-four patients with severe MS undergoing commissurotomy and 24 controls were studied. Electrophysiological evaluation was performed in 12 patients in each group by positioning multi-electrode catheters in both atria to determine the following: effective refractory period (ERP) at 10 sites at 600 and 450 ms; conduction time; conduction delay at the crista terminalis (CT); and vulnerability for atrial fibrillation (AF). P-wave duration (PWD) was determined on the surface ECG. In the remaining 12 patients in each group, electroanatomic maps of both atria were created to determine conduction velocity..

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University of Melbourne Researchers

Grants

Funding Acknowledgements

B.J. is supported by the Biosense-Webster Electrophysiology Scholarship from the University of Adelaide. M. K. S. is supported by the National Heart Foundation of New Zealand and the Dawes Scholarship from the Royal Adelaide Hospital. L. M. is supported by the Peter Doherty Fellowship, National Health and Medical Research Council of Australia. P. S. is supported by the National Heart Foundation of Australia.