Journal article

SMALL INTESTINAL DEVELOPMENT IN GROWTH-RETARDED FETAL SHEEP

CG AVILA, R HARDING, S REES, PM ROBINSON

Journal of Pediatric Gastroenterology and Nutrition | LIPPINCOTT-RAVEN PUBL | Published : 1989

Abstract

The functional maturity of the gastrointestinal system is essential for the survival of the neonate. The effects of reducing placental size and the ensuing fetal growth retardation on the development of the small intestine (SI) of the sheep fetus were investigated. At 140 days of gestation (term is 147 days), fetal body weight, gastrointestinal weight (from the abomasum to the rectum, i.e., the gut), SI weight, and SI length in the growth-retarded fetuses (n = 6) were significantly reduced (p less than 0.05) when compared with age- and breed-matched control fetuses. The SI weight was disproportionately reduced as a fraction of the gut weight or SI length (p less than 0.01). The proximal SI s..

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University of Melbourne Researchers