Journal article

Relationship between disease severity and quality of life and assessment of health care utilization and cost for ulcerative colitis in Australia: A cross-sectional, observational study

Peter R Gibson, Carolynne Vaizey, Christopher M Black, Rebecca Nicholls, Adele R Weston, Peter Bampton, Miles Sparrow, Ian C Lawrance, Warwick S Selby, Jane M Andrews, Alissa J Walsh, David J Hetzel, Finlay A Macrae, Gregory T Moore, Martin D Weltman, Rupert W Leong, Tao Fan

Journal of Crohn's and Colitis | ELSEVIER SCIENCE BV | Published : 2014

Abstract

BACKGROUND & AIMS: The burden of ulcerative colitis (UC) in relation to disease severity is not well documented. This study quantitatively evaluated the relationship between disease activity and quality of life (QoL), as well as health care utilization, cost, and work-related impairment associated with UC in an Australian population. METHODS: A cross-sectional, noninterventional, observational study was performed in patients with a wide range of disease severity recruited during routine specialist consultations. Evaluations included the Assessment of Quality of Life-8-dimension (AQoL-8D), EuroQol 5-dimension, 5-level (EQ-5D-5L), the disease-specific Inflammatory Bowel Disease Questionnaire (..

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Grants

Funding Acknowledgements

The authors thank Dr Paul Pavli, Canberra Hospital, Woden, Australian Capital Territory, Australia, who also served as an Investigator for the SOLUTION UC study. Medical writing and/or editorial assistance was provided by Ellen Stoltzfus, PhD, and Angela Cimmino, PharmD, of JK Communications, Inc., Conshohocken, PA. This assistance was funded by Merck Sharp & Dohme Corp., a subsidiary of Merck a Co., Inc., Whitehouse Station, NJ.Role of the study sponsor: Merck Sharp & Dohrne Corp., Whitehouse Station, New Jersey, USA, funded this study and participated in the study design, data collection, data management, data analysis and interpretation, and preparation of the manuscript. The authors are responsible for the content of the manuscript and approved the final draft for submission.