Giardia/giardiasis - A perspective on diagnostic and analytical tools
Anson V Koehler, Aaron R Jex, Shane R Haydon, Melita A Stevens, Robin B Gasser
Biotechnology Advances | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2014
Giardiasis is a gastrointestinal disease of humans and other animals caused by species of parasitic protists of the genus Giardia. This disease is transmitted mainly via the faecal-oral route (e.g., in water or food) and is of socioeconomic importance worldwide. The accurate detection and genetic characterisation of the different species and population variants (usually referred to as assemblages and/or sub-assemblages) of Giardia are central to understanding their transmission patterns and host spectra. The present article provides a background on Giardia and giardiasis, and reviews some key techniques employed for the identification and genetic characterisation of Giardia in biological sam..View full abstract
Funds from the Australian Research Council (ARC), the National Health and Medical Research Council (NHMRC) and Melbourne Water Corporation are gratefully acknowledged, as is support from the Alexander von Humboldt Foundation and the Freie University Berlin (RBG). Thanks are given to Georg von Samson-Himmelstjerna for comments on the manuscript. The authors also thank two anonymous reviewers for their constructive comments and suggestions. The authors have no conflict of interest.