Journal article

Neonatal Brain Pathology Predicts Adverse Attention and Processing Speed Outcomes in Very Preterm and/or Very Low Birth Weight Children

Andrea L Murray, Shannon E Scratch, Deanne K Thompson, Terrie E Inder, Lex W Doyle, Jacqueline FI Anderson, Peter J Anderson

Neuropsychology | AMER PSYCHOLOGICAL ASSOC | Published : 2014

Abstract

OBJECTIVE: This study aimed to examine attention and processing speed outcomes in very preterm (VPT; < 32 weeks' gestational age) or very low birth weight (VLBW; < 1,500 g) children, and to determine whether brain abnormality measured by neonatal MRI can be used to predict outcome in these domains. METHOD: A cohort of 198 children born < 30 weeks' gestational age and/or < 1,250 g and 70 term controls were examined. Neonatal MRI scans at term equivalent age were quantitatively assessed for white matter, cortical gray matter, deep gray matter, and cerebellar abnormalities. Attention and processing speed were assessed at 7 years using standardized neuropsychological tests. Group differences wer..

View full abstract

Grants

Awarded by Australia's National Health & Medical Research Council


Awarded by National Institutes of Health


Awarded by EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH &HUMAN DEVELOPMENT


Funding Acknowledgements

We would like to acknowledge the input of the VIBeS research team, and all the families who participated in this study. This study was funded by Australia's National Health & Medical Research Council (Project Grants (237117 & 491209), Early Career Award (1012236 to D.T.), Senior Research Fellowship (628371 to P.A.)), National Institutes of Health (HD058056), and the Victorian Government's Operational Infrastructure Support Program. The information in this article and the manuscript itself has never been published either electronically or in print, and there are no conflicts of interest.