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Journal article

A Thr(357) to Ser polymorphism in homozygous and compound heterozygous subjects causes absent or reduced P2X(7) function and impairs ATP-induced mycobacterial killing by macrophages

AN Shemon, R Sluyter, SL Fernando, AL Clarke, LP Dao-Ung, KK Skarratt, BM Saunders, KS Tan, BJ Gu, SJ Fuller, WJ Britton, S Petrou, JS Wiley

The Journal of biological chemistry | AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC | Published : 2006

DOI: 10.1074/jbc.M507816200

University of Melbourne Researchers

Steven Petrou's Profile Picture
Steven Petrou Author Florey Department of Neuroscience and Mental Health

Ben Gu's Profile Picture
Ben Gu Author Florey Department of Neuroscience and Mental Health

Citation metrics

126Web of Science

Keywords

Animals
Mycobacterium Bovis
Cell Differentiation
Mutation
Biochemistry & Molecular Biology
L-Selectin
Receptors, Purinergic P2x7
Interferon-Gamma
Polymorphism, Single Nucleotide
Transfection
Pore Formation
Female
Macrophages
Mutagenesis, Site-Directed
Threonine
Gene
Electrophysiology
Polymorphism, Genetic
Alleles
Tuberculosis
Codon, Terminator
Serine
Cell Line
Oocytes
Phospholipase-D Activation
Life Sciences & Biomedicine
Barium
Mycobacterium
Of-Function
Receptors, Purinergic P2
Ethidium
Male
Xenopus Laevis
Human-Lymphocytes
Homozygote
Humans
Microscopy, Fluorescence
Purinergic Receptors
Lymphocytes
Flow Cytometry
Monocytes
Expression
Inhibition
Heterozygote
Science & Technology
Gene Frequency
Adenosine Triphosphate
Green Fluorescent Proteins

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